January 17, 2023
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Source/Disclosure
Disclosure:
Abella has consulted for Becton Dickinson, NeuroOptics, Stryker, and Zoll, and reportedly owns shares in MDAlly and VOC Health. All other authors did not report relevant financial disclosures.
According to a study published in , quantitative pupillometry may be a reliable method to assess clinically intoxicated patients with ED. Journal of the American College of Emergency Physicians Opens.
“It is already widely used in critical care settings, with documented applications in detecting nerve damage and determining the efficacy of various interventions. [quantitative pupillometry] It may offer value to emergency physicians as a noninvasive, rapid, and accurate diagnostic approach for use in the detection and treatment of intoxicated patients. ” Benjamin S. AbellaMD, MPhil, A professor and principal investigator of emergency medicine at the University of Pennsylvania, writes a colleague.
A recent study found that quantitative pupillometry may be a reliable method to measure responsiveness in patients with suspected drug addiction in the emergency department setting. Source: Adobe Stock
Abella and fellow researchers investigated the extent to which different quantitative pupillometry (QP) metrics were associated with different drug classes and investigated QP as a rapid assessment tool for intoxicated individuals within ED. I tried to research the benefits.
A prospective cohort study was conducted between February 25, 2019 and April 24, 2021, during which time 325 adults (median age 38 years, 34% female, 55 who presented with single-substance addiction). %) were clinically diagnosed or considered addicted. Dropping out patients were enrolled in the ED at the University of Pennsylvania Hospital and Penn Presbyterian Medical Center. Of those, 119 patients were included in the final dataset.
Abella and colleagues reported data from participants, including maximum and minimum pupillary diameter, contraction or percent change, maximum contraction speed, contraction latency, dilation speed, neurological pupillary index (NPi), and seven other composite metrics. We analyzed the eight QP metrics of The researchers compared this data with that of her 82 healthy controls (median age, 28 years, her 66% female) and combined Z-scores to generate the NPi value. generated.
The researchers found that NPi values were not significantly different between control and study groups (4.31 ± 0.32 vs 4.29 ± 0.49) and between individuals with and without urine drug screening for positive opioid use. (4.22 ± 0.52 vs 4.32). ± 0.48). The data further showed that all other QP indices in the study group were lower than in the control group, except for contraction latency.
“With approximately 95,000 alcohol-related deaths per year and more than 70,000 opioid-related drug overdose deaths in 2021 alone, emergency medical services and emergency departments are under pressure to rapidly assess, treat, and monitor addictions. We face unique challenges related to ,” Abella said in a related article. release. “This clearly demonstrates that the NPi is a reliable tool for assessing and triaging patients and is a useful indicator of neurological function regardless of addiction, including that caused by opioids, in the emergency department.” It’s the first study of addicts.”
