Illustrated by Lauren Boglio
The search for autism biomarkers continues, and as some researchers revealed last week on Twitter, “No diagnostic candidate #biomarkers of #neurodevelopmental disorders, including autism,” said Sam Cortese, Professor of Child and Adolescent Psychiatry at the University of Southampton, UK. world psychiatry Early this month.
Out in world psychiatry @WPA_ Psychiatry780 studies systematically reviewed: no diagnostic candidates #biomarkers for #neurodevelopment Impairments with specificity and sensitivity greater than 80% have been reproduced in independent studies. https://t.co/Us3mF7SMIW@SotonPsych @UoS_Medicine pic.twitter.com/AeJmkMiQ8t
— Samuel Cortese (@CorteseSamuele) January 14, 2023
Cortese and his colleagues reviewed 780 studies and found no biomarkers “reported in at least two independent studies providing evidence of sensitivity and specificity of at least 80%.” The results are the same as those featured in his December issue of his community newsletter.
“How does the threshold potential biomaker is it actually used? Seena Fazel, professor of forensic psychiatry at the University of Oxford, UK, asked about the 80% cutoff.
Interested in choosing an 80% cutoff for both sens and spec? Wouldn’t the threshold depend on how the potential biomaker is actually used?
— Sheena Fazel (@seenafazel) January 16, 2023
“same conclusion It will be made in 2030 or 2050,” wrote Martin Plöderl, a professor of psychiatry at the Paracelsus Medical School in Salzburg, Austria, in a quoted tweet.
I expect the same conclusion to be drawn in 2030 or 2050, but until then there will always be promising research results, new research methods, and larger research requests. https://t.co/2Rrxl44oNb
— Pfluft (@PloederlM) January 15, 2023
go ahead, new Nature A study published last week found that “a The Surprising Role of Dopamine As an educational signal during free exploration in mice,” tweeted Sandeep Robert Dutta, principal investigator and professor of neurobiology at Harvard University.
How Does the Brain Organize Spontaneous Behavior? @vulcnethologist @GillisDub @neurojaym), revealing a surprising role for dopamine as an educational signal during free exploration, even in the absence of an explicit task or extrinsic reward. https://t.co/SevJFObvwN
— Sundeep Robert Datta (@Datta_Lab) January 18, 2023
Dopamine in the dorsolateral striatum, a brain region important for motor learning and execution, “fluctuations of a ton during voluntary behavior,” explains Datta, whose fluctuations are “Structuring ongoing behavior causally, even without a task structure or reward. ”
There’s a lot stuffed in here, but let’s not forget that DLS DA fluctuates a lot during voluntary actions, and these fluctuations can occur in the absence of task structure or rewards during ongoing is to causally structure the actions of pic.twitter.com/WJiadGfdAR
— Sundeep Robert Datta (@Datta_Lab) January 18, 2023
Björn Brembs, professor of neurogenetics at the University of Regensburg in Germany, tweeted about the research, which he was already excited to see presented at Neuroscience 2022.really advance the field”
I was excited when I saw it on SfN! It really advances the field, congratulations!
— Bjorn Brembs???????????????? (@brembs) January 19, 2023
“Understand how spontaneous action is organized As we move toward a wireless, free-moving paradigm, it’s absolutely imperative to make that clear.
This looks very interesting. Understanding how spontaneous actions are organized is absolutely essential for clarity as we transition to a wireless, free-to-move paradigm. https://t.co/AlXLT01wWY
— David L. Barack (@DLBarack) January 18, 2023
Social media users talked about another recent survey last week. Children with certain rare neurodevelopmental genetic conditions are more likely to have sleep disorders than their unaffected siblings. translation psychiatry A study published this month.
??????????Brand New????????? We are pleased to share our research on sleep and mental health in children with rare neurodevelopmental genetic conditions https: //t.co/WVl4FYSBfK @CNGG Cardiff @G2MH_ network @bm_marianne
— Dr. Samuel Chawner (@ChawnerSamuel) January 12, 2023
Researcher Samuel Chauner, a psychology research fellow at Cardiff University in Wales, tweeted that people with sleep disorders are “more likely to experience mental health problems,” including autism. The results highlight the “possibility of”. Early intervention strategy About the psychiatric risks informed by sleep profiles,” added Chawner.
Children with sleep problems were more likely to experience mental health problems.Sleep disorders often have an early onset, highlighting the potential for early intervention strategies for psychiatric risk informed by sleep profiles.
— Dr. Samuel Chawner (@ChawnerSamuel) January 12, 2023
Finally, the Autism Science Foundation “announced its first recipients. Severe Autism Pilot GrantThe Foundation awarded grants to four projects that “examine ways to improve sleep, neuropsychiatric regression, self-harm, and access to communication systems in people with severe autism.”
The Autism Science Foundation has announced the recipients of its first Severe Autism Pilot Grant. This unique funding mechanism supports research on people with autism who are most in need of support. I’m here. Read the press release: https://t.co/5ZPl2QVfyL#autism #profound autism #Science pic.twitter.com/9rjy7WdYIX
—ASF (@AutismScienceFd) January 11, 2023
Anne Roux, director of The Policy Impact Project in Philadelphia, Pennsylvania, tweeted: improve people’s lives”
This focus actually moves us towards improving people’s lives. Thank you very much! I am particularly excited about neuroinflammation research.
— Ann Lou, MPH (@annemroux) January 14, 2023
That’s it for this week’s community newsletter. If you have any interesting social his post suggestions that you have seen in the autism research field, feel free to email me. [email protected].
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