Professor Jeffrey D. Macklis
Oxford Martin Program on 3D Printing for Brain Repair, Oxford Martin Visiting Scholar
Jeffrey D. Macklis is Max and Anne Wien Professor of Life Sciences at Harvard University, Professor of Stem Cell and Regenerative Biology in the Department of Stem Cell and Regenerative Biology, Center for Brain Science, and Professor of Neurology. [Neuroscience] at Harvard Medical School (HMS). He had founded the Neuroscience Program Director at the Harvard Stem Cell Institute. He is Director of Graduate Studies in the Department of Stem Cell and Regenerative Biology and (Co-)Director of PhD in Developmental and Regenerative Biology. Harvard University program. He is an MIT-affiliated faculty member and MD-Ph.D. in the Department of Health Sciences and Technology (HST) at Harvard’s Massachusetts Institute of Technology (MIT). program.
His lab is directed to both: 1) Understanding the molecular control and mechanisms for neuronal subtype specification, development, diversity, formation of axon guidance circuits, and degeneration in the cerebral cortex. 2) Applying developmental control to regeneration and directed differentiation of both the brain and spinal cord in vitro Therapeutic and mechanical screening. The lab focuses on the development and subtype specification of neocortical projection neurons. Neuronal intracellular molecular mechanisms for subtype- and stage-specific circuit formation, maintenance, and function. Neural progenitor/“stem cell” biology. Induction of adult cortical neurogenesis; subtype-specific axonal growth cone biology. Direct differentiation of neuronal subtypes through molecular manipulation of neural progenitor and pluripotent cells (ES/iPS).
As an undergraduate, he attended MIT (SB Bioelectrical Engineering; SB Literature), Harvard Medical School (Harvard-MIT HST Program), and graduate school at MIT within HST, a student of Richard L. Sidman. He served as a postdoctoral fellow in developmental neuroscience at his HMS and received clinical training in neurology at Brigham and Women’s Hospital (BWH) in Internal Medicine and the Harvard Neurology Training Program (not clinically active). ).
He has received numerous awards and honors, including the Rita Allen Foundation Scholar Award, the Director’s Innovation Award from the NIH Director’s Office, the CNS Foundation Award, and the Senator Jacob Javits (MERIT) Award in Neuroscience from NINDS/NIH. I’m here. , the Cajal-Krieg Cortical Discoverer Prize, and a series of undergraduate and graduate teaching and research leadership awards over the past 25 years. He is an Allen Fellow of the Paul G. Allen Frontiers Group, a Brain Research Foundation Fellow, and has received his NIH Pioneer Award from the NIH Director’s Office.
