Brain Wealthy
    What's Hot

    Global Accessibility Awareness Day: Building Accessibility into Technology | By Ed Lovelock | Starship Technologies | May 2023

    May 18, 2023

    Providing a greener future.On this Earth Day we encourage… | Redete Nardos | | Starship Technologies | April 2023

    April 21, 2023

    Starship Technologies Sets New World Record with 10 Million Kilometers | Reed Zula | | Starship Technologies | April 2023

    April 3, 2023
    Facebook Twitter Instagram
    Facebook Twitter Instagram
    Brain Wealthy
    • Home
    • Anxiety

      FSU psychologist receives $3.7 million grant to combat anxiety in seniors with Alzheimer’s and cognitive impairment

      February 2, 2023

      How anxiety came to dominate the big business of medical marijuana cards in Pa.

      February 2, 2023

      How to Reduce Anxiety in Stressful Situations

      February 2, 2023

      The cat in boots The last wish taught me about anxiety

      February 2, 2023

      Inseparable cat trio with ‘separation anxiety brothers’ find new home

      February 2, 2023
    • Emotion

      Leigh-Anne Pinnock shares emotional post about embarking on her solo career

      February 2, 2023

      Ontario paramedic emotional during last radio call

      February 2, 2023

      A Pianist Faces Death and Recorded Music of Unspeakable Emotions

      February 2, 2023

      Return of home post linking Gichaara to ancestors is emotional for north coast nation

      February 2, 2023

      Mother of two sues New York school district for ‘mental distress’ caused by mask enforcement

      February 2, 2023
    • Neurology

      Gardasil Injection Lawsuit Claims HPV Vaccine Caused Neurological and Autonomic Dysfunction

      February 2, 2023

      REGENXBIO’s Duchenne Therapy RGX-202 Clinical Trial Begins Patient Recruitment

      February 2, 2023

      Aducanumab for the treatment of Alzheimer’s disease

      February 2, 2023

      Potential for Effective Comparative Studies and Treatment Approval in Epilepsy Care: Anup Patel, MD

      February 2, 2023

      Head injury does not predict memory impairment in NFL retirees, UT Southwestern study shows: Newsroom

      February 2, 2023
    • Sleep

      Review: Never Sleep Again: The Elm Street Legacy – Blu-ray

      February 2, 2023

      Get a better night’s sleep with better pillows from The Pillow Bar in Dallas

      February 2, 2023

      Is it okay to sleep with a necklace on?

      February 2, 2023

      Does tart cherry juice improve sleep?

      February 2, 2023

      Social Jet Lag, Sleep Chronotypes, and Why We Gotta Close Our Eyes and Embrace It

      February 2, 2023
    • Brain Research

      spark!Talk – video available online

      February 2, 2023

      Studies have found that obesity-related neurodegeneration mimics Alzheimer’s disease.newsroom

      February 2, 2023

      The Brain Observatory: New Museum to Participate in Museum Month

      February 1, 2023

      who wants to live forever

      February 1, 2023

      UK company makes surprise forays

      February 1, 2023
    • Brain Wealth
      1. Mental Health
      2. View All

      Research project applies a global lens to student mental health

      February 2, 2023

      DC Metro shooting suspect undergoes mental health evaluation after rampage

      February 2, 2023

      Gov. Ho-Chol unveils details of $1 billion plan to overhaul New York State’s mental health care continuum

      February 2, 2023

      Boston, we have a problem: data on mental health and practice come in

      February 2, 2023

      Research project applies a global lens to student mental health

      February 2, 2023

      DC Metro shooting suspect undergoes mental health evaluation after rampage

      February 2, 2023

      Gov. Ho-Chol unveils details of $1 billion plan to overhaul New York State’s mental health care continuum

      February 2, 2023

      Boston, we have a problem: data on mental health and practice come in

      February 2, 2023
    Brain Wealthy
    Home»Brain Research»A BBRC team finds that a genetic predisposition to longer telomeres may have a protective effect against Alzheimer’s disease.Atalaya
    Brain Research

    A BBRC team finds that a genetic predisposition to longer telomeres may have a protective effect against Alzheimer’s disease.Atalaya

    brainwealthy_vws1exBy brainwealthy_vws1exDecember 29, 2022No Comments4 Mins Read
    Facebook Twitter LinkedIn Telegram Pinterest Tumblr Reddit WhatsApp Email
    Share
    Facebook Twitter LinkedIn Pinterest Email


    Two studies conducted by the Barcelona Beta Brain Research Center (BBRC), a research center of the Pascual Malagall Foundation, involved participants in the ALFA study promoted by the ‘La Caixa’ foundation and found that telomere length Roles are evaluated.Markers of biological age, risk of neurodegenerative diseases and Alzheimer’s diseaseThe results of this study indicate that genetic mutations associated with longer telomere length may be associated with a reduced risk of developing Alzheimer’s disease. These genetic variants were associated with decreased levels of Alzheimer’s disease biomarkers, such as the p-tau protein, and increased cortical thickness in cognitively healthy people with a high genetic predisposition to Alzheimer’s disease. .

    “Telomeres are repetitive DNA sequences located at the ends of chromosomes. Their main function is to protect telomeres and prevent wear and tear.” BBRC researcher Blanca Rodríguez-Fernández, lead author of both studies, explains: “Over time, telomeres shorten each time a cell divides, so telomere length is considered an indicator of biological age,” she adds.

    The first study, published in the Computational and Structural Biotechnology Journal, suggests genetic mutations associated with longer telomeres. It may have a protective effect against the risk of developing Alzheimer’s disease and is significantly associated with increased life expectancy.

    MeA second study, published in Alzheimer’s Research & Therapy and published in collaboration with researchers from the Institute for Biomedical Research at Bellvitge Hospital, analyzed this possible relationship through the brain., cognitive and cerebrospinal fluid biomarkers of Alzheimer’s disease and neurodegeneration. This pioneering study used samples from participants in his ALFA study, a cohort containing a population of cognitively healthy individuals at risk for Alzheimer’s disease.

        Natalia-Vilor-Tejedor-lider-del-equipo-de-Neurobiogenetica-del-BBRC
    Natàlia Vilor-Tejedor, senior collaborator on this study and leader of the BBRC Neurobiogenetics team.

    The main results of this study reveal an important link between longer telomere length and genetic variants that predict reduced levels of several Alzheimer’s disease biomarkers., ptau protein, etc. Furthermore, inheriting longer telomeres is associated with increased cortical thickness among people with a genetic predisposition to Alzheimer’s disease in the future.

    Natalia Vilor-Tejedor, a senior collaborator on the study and leader of the BBRC Neurobiogenetics team, explains: “Gene variants associated with longer telomere length may protect brain structures through multiple mechanisms, either in regions affected primarily by processes associated with Alzheimer’s disease or aging itself.”.

    Continuation of these studies is key to understanding the role of telomere length in the development of Alzheimer’s diseaseAs BBRC collaborator and project co-leader Dr. Marta Crous-Bou points out, the findings are positive, but “these include participants at different stages of disease development, It should also be replicated in larger cohorts, as a follow-up and additional observational analysis of ALFA study participants to better understand the results obtained and the underlying biological mechanisms.”

    bibliographic reference

    Rodríguez-Fernández, B., Gispert, JD, Guigo, R., Navarro, A., Vilor-Tejedor, N. & Crous-Bou, M. (2022b). Relationships with degenerative diseases and life expectancy. Computational and Structural Biotechnology Journal, 20, 4251-4256. https://doi.org/10.1016/j.csbj.2022.08.006

    Rodríguez-Fernández, B., Vilor-Tejedor, N., Arenaza-Urquijo, EM, Sánchez-Benavides, G., Suárez-Calvet, M., Operto, G., Minguillón, C., Fauria, K., Kollmorgen , G., Suridjan, I., de Moura, MC, Piñeyro, D., Esteller, M., Blennow, K., Zetterberg, H., De Vivo, I., Molinuevo, JL, Navarro, A., Gispert , J.D., Sala-Vila, A., Crous-Bou M. (2022). Genetically predicted telomere length and the endophenotype of Alzheimer’s disease: a Mendelian randomized study. Research and Treatment of Alzheimer’s Disease, 14(1). https://doi.org/10.1186/s13195-022-01101-9

    About Alzheimer’s disease

    A new case of dementia is diagnosed every three seconds worldwide and it is estimated that 50 million people are currently suffering from dementia, mostly due to Alzheimer’s disease. In Spain, this figure translates to her over 900,000 people affected. As the latest World Alzheimer Report 2018, published by Alzheimer’s Disease International, notes that life expectancy is increasing, the number of cases could drop to 3 by 2050 if no treatment is found to prevent or slow the progression of the disease. It can double and reach epidemic proportions. .

    About the Barcelona βeta Brain Research Center and the Pascual Malagall Foundation The Barcelona βeta

    The Brain Research Center (BBRC) is a research center of the Pascual Malagal Foundation, promoted by the “La Caixa” Foundation since its inception, dedicated to the prevention of Alzheimer’s disease and the study of cognitive functions affected by healthy and morbid aging. doing. The Pascual Malagall Foundation is a non-profit organization established in April 2008 in response to the commitment of former Barcelona Mayor and former Catalonia President Pascual Malagall when he publicly announced that he had been diagnosed with an illness. Alzheimer’s disease. The Foundation’s mission is to advance research to prevent Alzheimer’s disease and provide solutions that improve the quality of life for those affected and their caregivers.



    Source link

    Share. Facebook Twitter Pinterest LinkedIn Tumblr Telegram Email
    Previous ArticleWoman Founds Nonprofit To Help Others Fight Mental Health Issues – NBC Los Angeles
    Next Article Child survivors of firearm injuries are more likely to receive a mental health diagnosis within a year
    brainwealthy_vws1ex
    • Website

    Related Posts

    spark!Talk – video available online

    February 2, 2023

    Studies have found that obesity-related neurodegeneration mimics Alzheimer’s disease.newsroom

    February 2, 2023

    The Brain Observatory: New Museum to Participate in Museum Month

    February 1, 2023
    Add A Comment

    Leave A Reply Cancel Reply

    Top Posts

    Subscribe to Updates

    Get the latest sports news from SportsSite about soccer, football and tennis.

    This website provides information about Brain and other things. Keep Supporting Us With the Latest News and we Will Provide the Best Of Our To Makes You Updated All Around The World News. Keep Sporting US.

    Facebook Twitter Instagram Pinterest YouTube
    Top Insights

    Top UK Stocks to Watch: Capita Shares Rise as it Unveils

    January 15, 2021
    8.5

    Digital Euro Might Suck Away 8% of Banks’ Deposits

    January 12, 2021

    Oil Gains on OPEC Outlook That U.S. Growth Will Slow

    January 11, 2021
    Get Informed

    Subscribe to Updates

    Get the latest creative news from FooBar about art, design and business.

    © 2023 brainwealthy. Designed by brainwealthy.
    • Home
    • Contact us
    • DMCA
    • Privacy Policy

    Type above and press Enter to search. Press Esc to cancel.